Fibroblast activation is a research area focused on understanding the molecular mechanisms that regulate the activation and function of fibroblasts, a type of cell found in connective tissue. Fibroblasts play a crucial role in wound healing, tissue repair, and the development of fibrotic diseases. Activation of fibroblasts can lead to the production of extracellular matrix proteins, growth factors, and cytokines, which can contribute to tissue remodeling and inflammation. Research in this area aims to identify potential therapeutic targets for the treatment of fibrotic diseases, such as pulmonary fibrosis, liver cirrhosis, and systemic sclerosis.